Strand bias in complementary single-nucleotide polymorphisms of transcribed human sequences: evidence for functional effects of synonymous polymorphisms

BACKGROUND: Complementary single-nucleotide polymorphisms (SNPs) may not be distributed equally between two DNA strands if the strands are functionally distinct, such as in transcribed genes. In introns, an excess of A↔G over the complementary C↔T substitutions had previously been found and attribut...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Hui-Qi, Lawrence, Steve G, Guo, Fan, Majewski, Jacek, Polychronakos, Constantin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559705/
https://www.ncbi.nlm.nih.gov/pubmed/16916449
http://dx.doi.org/10.1186/1471-2164-7-213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559705/
https://www.ncbi.nlm.nih.gov/pubmed/16916449
http://dx.doi.org/10.1186/1471-2164-7-213

Ejemplares similares