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Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi) In Vivo

RNA interference (RNAi) is a powerful method for specific gene silencing which may also lead to promising novel therapeutic strategies. It is mediated through small interfering RNAs (siRNAs) which sequence-specifically trigger the cleavage and subsequent degradation of their target mRNA. One critica...

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Detalles Bibliográficos
Autor principal: Aigner, Achim
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559929/
https://www.ncbi.nlm.nih.gov/pubmed/17057369
http://dx.doi.org/10.1155/JBB/2006/71659