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Alterations in gene expression in T1α null lung: a model of deficient alveolar sac development
BACKGROUND: Development of lung alveolar sacs of normal structure and size at late gestation is necessary for the gas exchange process that sustains respiration at birth. Mice lacking the lung differentiation gene T1α [T1α(-/-)] fail to form expanded alveolar sacs, resulting in respiratory failure a...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562362/ https://www.ncbi.nlm.nih.gov/pubmed/16869965 http://dx.doi.org/10.1186/1471-213X-6-35 |