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Alterations in gene expression in T1α null lung: a model of deficient alveolar sac development

BACKGROUND: Development of lung alveolar sacs of normal structure and size at late gestation is necessary for the gas exchange process that sustains respiration at birth. Mice lacking the lung differentiation gene T1α [T1α(-/-)] fail to form expanded alveolar sacs, resulting in respiratory failure a...

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Detalles Bibliográficos
Autores principales: Millien, Guetchyn, Spira, Avrum, Hinds, Anne, Wang, Junling, Williams, Mary C, Ramirez, Maria I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562362/
https://www.ncbi.nlm.nih.gov/pubmed/16869965
http://dx.doi.org/10.1186/1471-213X-6-35