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Increased large conductance calcium-activated potassium (BK) channel expression accompanied by STREX variant downregulation in the developing mouse CNS

BACKGROUND: Large conductance calcium- and voltage activated potassium (BK) channels are important determinants of neuronal excitability through effects on action potential duration, frequency and synaptic efficacy. The pore- forming subunits are encoded by a single gene, KCNMA1, which undergoes ext...

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Detalles Bibliográficos
Autores principales: MacDonald, Stephen H-F, Ruth, Peter, Knaus, Hans-Guenther, Shipston, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562363/
https://www.ncbi.nlm.nih.gov/pubmed/16872513
http://dx.doi.org/10.1186/1471-213X-6-37