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The E670G SNP in the PCSK9 gene is associated with polygenic hypercholesterolemia in men but not in women
BACKGROUND: Common genetic variants in the PCSK9 gene have been reported to be associated with both elevated and exceptionally low LDL levels. The association of a common haplotype, encompassing the E670G single nucleotide polymorphism, with LDL levels reported by Chen et al (J Am Coll Cardiol 2005;...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562364/ https://www.ncbi.nlm.nih.gov/pubmed/16875509 http://dx.doi.org/10.1186/1471-2350-7-66 |