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The structure of IL2 bound to the three chains of the IL2 receptor and how signaling occurs

The interleukin-2 molecule and receptor were the first of the interleukins to be discovered and characterized at the molecular level. Now after 20 years of effort, two groups have succeeded in determining the structure of IL2 bound to the external domains of the three receptor chains in a quaternary...

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Detalles Bibliográficos
Autor principal: Smith, Kendall A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562422/
https://www.ncbi.nlm.nih.gov/pubmed/16907989
http://dx.doi.org/10.1186/1476-9433-5-3