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Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation

Reinforcement learning theorizes that strengthening of synaptic connections in medium spiny neurons of the striatum occurs when glutamatergic input (from cortex) and dopaminergic input (from substantia nigra) are received simultaneously. Subsequent to learning, medium spiny neurons with strengthened...

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Detalles Bibliográficos
Autores principales: Lindskog, Maria, Kim, MyungSook, Wikström, Martin A, Blackwell, Kim T, Kotaleski, Jeanette Hellgren
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1562452/
https://www.ncbi.nlm.nih.gov/pubmed/16965177
http://dx.doi.org/10.1371/journal.pcbi.0020119