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Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition
Prostaglandins (PGs) are requisite components of inflammatory pain as indicated by the efficacy of cyclooxygenase 1/2 (COX1/2) inhibitors. PGs do not activate nociceptive ion channels directly, but sensitize them by downstream mechanisms linked to G-protein coupled receptors. Antiinflammatory effect...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563450/ https://www.ncbi.nlm.nih.gov/pubmed/16916451 http://dx.doi.org/10.1186/1744-8069-2-26 |