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Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition

Prostaglandins (PGs) are requisite components of inflammatory pain as indicated by the efficacy of cyclooxygenase 1/2 (COX1/2) inhibitors. PGs do not activate nociceptive ion channels directly, but sensitize them by downstream mechanisms linked to G-protein coupled receptors. Antiinflammatory effect...

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Detalles Bibliográficos
Autores principales: Premkumar, Louis S, Raisinghani, Manish
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563450/
https://www.ncbi.nlm.nih.gov/pubmed/16916451
http://dx.doi.org/10.1186/1744-8069-2-26

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