Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets

BACKGROUND: Targeting persistent tubercule bacilli has become an important challenge in the development of anti-tuberculous drugs. As the glyoxylate bypass is essential for persistent bacilli, interference with it holds the potential for designing new antibacterial drugs. We have developed kinetic m...

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Detalles Bibliográficos
Autores principales: Singh, Vivek Kumar, Ghosh, Indira
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563452/
https://www.ncbi.nlm.nih.gov/pubmed/16887020
http://dx.doi.org/10.1186/1742-4682-3-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563452/
https://www.ncbi.nlm.nih.gov/pubmed/16887020
http://dx.doi.org/10.1186/1742-4682-3-27

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