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The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6(+/- )mouse model of epithelial wound-healing delay

BACKGROUND: Congenital aniridia caused by heterozygousity at the PAX6 locus is associated with ocular surface disease including keratopathy. It is not clear whether the keratopathy is a direct result of reduced PAX6 gene dosage in the cornea itself, or due to recurrent corneal trauma secondary to de...

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Detalles Bibliográficos
Autores principales: Leiper, Lucy J, Walczysko, Petr, Kucerova, Romana, Ou, Jingxing, Shanley, Lynne J, Lawson, Diane, Forrester, John V, McCaig, Colin D, Zhao, Min, Collinson, J Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563477/
https://www.ncbi.nlm.nih.gov/pubmed/16914058
http://dx.doi.org/10.1186/1741-7007-4-27