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Stochastic mRNA Synthesis in Mammalian Cells

Individual cells in genetically homogeneous populations have been found to express different numbers of molecules of specific proteins. We investigated the origins of these variations in mammalian cells by counting individual molecules of mRNA produced from a reporter gene that was stably integrated...

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Detalles Bibliográficos
Autores principales: Raj, Arjun, Peskin, Charles S, Tranchina, Daniel, Vargas, Diana Y, Tyagi, Sanjay
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563489/
https://www.ncbi.nlm.nih.gov/pubmed/17048983
http://dx.doi.org/10.1371/journal.pbio.0040309