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Inhibition of Gap Junction Communication at Ectopic Eph/ephrin Boundaries Underlies Craniofrontonasal Syndrome

Mutations in X-linked ephrin-B1 in humans cause craniofrontonasal syndrome (CFNS), a disease that affects female patients more severely than males. Sorting of ephrin-B1–positive and –negative cells following X-inactivation has been observed in ephrin-B1(+/−) mice; however, the mechanisms by which mo...

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Detalles Bibliográficos
Autores principales: Davy, Alice, Bush, Jeffrey O, Soriano, Philippe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563491/
https://www.ncbi.nlm.nih.gov/pubmed/16968134
http://dx.doi.org/10.1371/journal.pbio.0040315