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Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism

HMG-CoA reductase and the LDL receptor are ubiquitously expressed in major tissues. Since the liver plays a major role in regulating circulating LDL, it is usually of interest to measure the effects of drug or dietary interventions on these proteins in liver. In humans, peripheral blood mononuclear...

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Detalles Bibliográficos
Autores principales: Aggarwal, Dimple, Freake, Hedley C, Soliman, Ghada A, Dutta, Amrita, Fernandez, Maria-Luz
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564017/
https://www.ncbi.nlm.nih.gov/pubmed/16911794
http://dx.doi.org/10.1186/1476-511X-5-22