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Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism
HMG-CoA reductase and the LDL receptor are ubiquitously expressed in major tissues. Since the liver plays a major role in regulating circulating LDL, it is usually of interest to measure the effects of drug or dietary interventions on these proteins in liver. In humans, peripheral blood mononuclear...
Autores principales: | Aggarwal, Dimple, Freake, Hedley C, Soliman, Ghada A, Dutta, Amrita, Fernandez, Maria-Luz |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564017/ https://www.ncbi.nlm.nih.gov/pubmed/16911794 http://dx.doi.org/10.1186/1476-511X-5-22 |
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