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Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells

BACKGROUND: We previously identified a set of genes called ECATs (ES cell-associated transcripts) that are expressed at high levels in mouse ES cells. Here, we examine the expression and DNA methylation of ECATs in somatic cells and germ cells. RESULTS: In all ECATs examined, the promoter region had...

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Detalles Bibliográficos
Autores principales: Imamura, Masanori, Miura, Kyoko, Iwabuchi, Kumiko, Ichisaka, Tomoko, Nakagawa, Masato, Lee, Jiyoung, Kanatsu-Shinohara, Mito, Shinohara, Takashi, Yamanaka, Shinya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564388/
https://www.ncbi.nlm.nih.gov/pubmed/16859545
http://dx.doi.org/10.1186/1471-213X-6-34