Flow-cytometric assessment of cellular poly(ADP-ribosyl)ation capacity in peripheral blood lymphocytes

BACKGROUND: Poly(ADP-ribosyl)ation is a posttranslational modification of nuclear proteins catalysed by poly(ADP-ribose) polymerases (PARPs), using NAD(+ )as a substrate. Activation of PARP-1 is in immediate response to DNA damage generated by endogenous and exogenous damaging agents. It has been im...

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Detalles Bibliográficos
Autores principales: Kunzmann, Andrea, Liu, Dan, Annett, Kathryn, Malaisé, Muriel, Thaa, Bastian, Hyland, Paul, Barnett, Yvonne, Bürkle, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564410/
https://www.ncbi.nlm.nih.gov/pubmed/16854233
http://dx.doi.org/10.1186/1742-4933-3-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564410/
https://www.ncbi.nlm.nih.gov/pubmed/16854233
http://dx.doi.org/10.1186/1742-4933-3-8

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