Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus

The tumor suppressor gene Apc (adenomatous polyposis coli) is a member of the Wnt signaling pathway that is involved in development and tumorigenesis. Heterozygous knockout mice for Apc have a tumor predisposition phenotype and homozygosity leads to embryonic lethality. To understand the role of Apc...

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Detalles Bibliográficos
Autores principales: Kuraguchi, Mari, Wang, Xiu-Ping, Bronson, Roderick T, Rothenberg, Rebecca, Ohene-Baah, Nana Yaw, Lund, Jennifer J, Kucherlapati, Melanie, Maas, Richard L, Kucherlapati, Raju
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564426/
https://www.ncbi.nlm.nih.gov/pubmed/17002498
http://dx.doi.org/10.1371/journal.pgen.0020146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564426/
https://www.ncbi.nlm.nih.gov/pubmed/17002498
http://dx.doi.org/10.1371/journal.pgen.0020146

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