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Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications

BACKGROUND: Both phenotypic and cytogenetic variability have been reported for clones of breast carcinoma cell lines but have not been comprehensively studied. Despite this, cell lines such as MCF-7 cells are extensively used as model systems. METHODS: In this work we documented, using CGH and RNA e...

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Detalles Bibliográficos
Autores principales: Nugoli, Mélanie, Chuchana, Paul, Vendrell, Julie, Orsetti, Béatrice, Ursule, Lisa, Nguyen, Catherine, Birnbaum, Daniel, Douzery, Emmanuel JP, Cohen, Pascale, Theillet, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156633/
https://www.ncbi.nlm.nih.gov/pubmed/12713671
http://dx.doi.org/10.1186/1471-2407-3-13