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Accumulation of large non-circular forms of the chromosome in recombination-defective mutants of Escherichia coli

BACKGROUND: Double-strand breakage of chromosomal DNA is obviously a serious threat to cells because various activities of the chromosome depend on its integrity. However, recent experiments suggest that such breakage may occur frequently during "normal" growth in various organisms – from...

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Detalles Bibliográficos
Autores principales: Handa, Naofumi, Kobayashi, Ichizo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156651/
https://www.ncbi.nlm.nih.gov/pubmed/12718760
http://dx.doi.org/10.1186/1471-2199-4-5