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p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing.
In vivo carcinogenicity testing is an expensive and time-consuming process, and as a result, only a relatively small fraction of new and existing chemicals has been tested in this manner. Therefore, the development and validation of alternative approaches is desirable. We previously developed a mamm...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566603/ https://www.ncbi.nlm.nih.gov/pubmed/10504146 |