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p53 induction as a genotoxic test for twenty-five chemicals undergoing in vivo carcinogenicity testing.

In vivo carcinogenicity testing is an expensive and time-consuming process, and as a result, only a relatively small fraction of new and existing chemicals has been tested in this manner. Therefore, the development and validation of alternative approaches is desirable. We previously developed a mamm...

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Detalles Bibliográficos
Autores principales: Duerksen-Hughes, P J, Yang, J, Ozcan, O
Formato: Texto
Lenguaje:English
Publicado: 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566603/
https://www.ncbi.nlm.nih.gov/pubmed/10504146