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Physiologically based pharmacokinetic model for the inhibition of acetylcholinesterase by organophosphate esters.

Organophosphate (OP) exposure can be lethal at high doses while lower doses may impair performance of critical tasks. The ability to predict such effects for realistic exposure scenarios would greatly improve OP risk assessment. To this end, a physiologically based model for diisopropylfluorophospha...

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Detalles Bibliográficos
Autores principales: Gearhart, J M, Jepson, G W, Clewell, H J, Andersen, M E, Conolly, R B
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566752/
https://www.ncbi.nlm.nih.gov/pubmed/7737042