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Development of methods to monitor exposure to 1-nitropyrene.

On the basis of 32P-postlabeling analysis, treatment of rats with 1-nitropyrene (1-NP) resulted in the formation of multiple DNA adducts in the liver, mammary glands, and peripheral lymphocytes. The one adduct resulting from nitroreduction, N-(deoxyguanosin-8-yl)-1-aminopyrene, constitutes only a mi...

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Detalles Bibliográficos
Autores principales: el-Bayoumy, K, Johnson, B, Roy, A K, Upadhyaya, P, Partian, S, Hecht, S S
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566839/
https://www.ncbi.nlm.nih.gov/pubmed/7889855