Biphasic removal of DNA adducts in a repetitive DNA sequence after dietary administration of 2-acetylaminofluorene.

Dietary administration of the hepatocarcinogen 2-acetylaminofluorene (2-AAF) to rats results in the formation of a major hepatic DNA adduct, N-(deoxyguanosin-8-yl)-2-aminofluorene (dG-C8-AF). In liver DNA, dG-C8-AF reaches steady-state conditions after approximately 2 weeks of feeding and is removed...

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Detalles Bibliográficos
Autores principales: Culp, S J, Poirier, M C, Beland, F A
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567074/
https://www.ncbi.nlm.nih.gov/pubmed/8319642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567074/
https://www.ncbi.nlm.nih.gov/pubmed/8319642

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