Cardiac damage induced by 2-amino-3-methyl-imidazo[4,5-f]quinoline in nonhuman primates.

The heterocyclic aromatic amine 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) is a potent hepatocarcinogen in cynomolgus and rhesus monkeys. The finding of high cardiac IQ-DNA adduct levels prompted a histopathological study of perfusion-fixed hearts from 10 tumor-bearing monkeys chronically dosed wi...

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Detalles Bibliográficos
Autores principales: Thorgeirsson, U P, Farb, A, Virmani, R, Adamson, R H
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567181/
https://www.ncbi.nlm.nih.gov/pubmed/8033851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567181/
https://www.ncbi.nlm.nih.gov/pubmed/8033851

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