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Effects of metal treatment on DNA repair in polyamine-depleted HeLa cells with special reference to nickel.
Human cells depleted of the naturally occurring polyamines putrescine, spermidine, and spermine exhibit altered chromatin structure and marked deficiencies in DNA replicative and repair processes. Similar effects have been observed following treatment of normal mammalian cells with various heavy met...
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Formato: | Texto |
Lenguaje: | English |
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1994
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567407/ https://www.ncbi.nlm.nih.gov/pubmed/7843137 |