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Nickel-induced alterations in human renal epithelial cells.

Cellular progression to malignancy appears to require a number of distinct steps in which genetic damage in key regulatory genes accumulates. Immortalization, or escape from senescence, is considered to be one of the first phenotypic changes. Ni2+ treatment of normal human kidney epithelial (NHKE) c...

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Detalles Bibliográficos
Autores principales: Haugen, A, Maehle, L, Mollerup, S, Rivedal, E, Ryberg, D
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567418/
https://www.ncbi.nlm.nih.gov/pubmed/7843084