Quantitative predictability of carcinogenicity of the covalent binding index of chemicals to DNA: comparison of the in vivo and in vitro assays.

The capability of covalent binding to DNA to predict the initiating potential of chemical carcinogens was compared for the assays performed in vivo (rodent liver DNA) and in vitro (purified DNA incubated in the presence of mouse and rat liver microsomes). A quantitative correlation between DNA adduc...

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Detalles Bibliográficos
Autores principales: Taningher, M, Saccomanno, G, Santi, L, Grilli, S, Parodi, S
Formato: Texto
Lenguaje:English
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567642/
https://www.ncbi.nlm.nih.gov/pubmed/2351121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567642/
https://www.ncbi.nlm.nih.gov/pubmed/2351121

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