Metabolism and mutagenicity of isoprene.

Liver microsomes of various rodents (mouse, rat, rabbit, and hamster) metabolize isoprene (2-methyl-1,3-butadiene) to the corresponding monoepoxides 3,4-epoxy-3-methyl-1-butene and 3,4-epoxy-2-methyl-1-butene. 3,4-Epoxy-3-methyl-1-butene (half-life 85 min) was found to be the main metabolite, althou...

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Detalles Bibliográficos
Autores principales: Gervasi, P G, Longo, V
Formato: Texto
Lenguaje:English
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567766/
https://www.ncbi.nlm.nih.gov/pubmed/2401275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567766/
https://www.ncbi.nlm.nih.gov/pubmed/2401275

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