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Assessment of the propensity for covalent binding of electrophiles to biological substrates.
Electrophilic character is associated with the ability of external agents to interact with centers of electron density in biological macromolecules and to cause the interruption or alternation of normal activity. With the observation of site specificity in mutagenic events. Pearson's hard/soft...
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| Formato: | Texto |
| Lenguaje: | English |
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1990
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567832/ https://www.ncbi.nlm.nih.gov/pubmed/2269229 |