A mechanism of haloalkene-induced renal carcinogenesis.

Several halogenated alkenes are nephrotoxic; some others induce renal tubular adenocarcinomas in rodents after lifelong administration. A bioactivation mechanism accounting for the organ-selective tumor induction has been elucidated: conjugation of the parent compounds with glutathione (GSH), cataly...

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Detalles Bibliográficos
Autores principales: Dekant, W, Vamvakas, S, Koob, M, Köchling, A, Kanhai, W, Müller, D, Henschler, D
Formato: Texto
Lenguaje:English
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567982/
https://www.ncbi.nlm.nih.gov/pubmed/2272303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567982/
https://www.ncbi.nlm.nih.gov/pubmed/2272303

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