Stereoselective metabolism of dibenz(a,h)anthracene to trans-dihydrodiols and their activation to bacterial mutagens.

Dibenz(a,h)anthracene (DBA), a carcinogenic, polycyclic aromatic hydrocarbon ubiquitous in the environment, is metabolized by the hepatic microsomal fraction of immature Sprague-Dawley rats pretreated with Aroclor 1254 to 27 ethyl acetate-extractable metabolites. More than half of these metabolites...

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Detalles Bibliográficos
Autores principales: Platt, K L, Schollmeier, M, Frank, H, Oesch, F
Formato: Texto
Lenguaje:English
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568004/
https://www.ncbi.nlm.nih.gov/pubmed/2272331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568004/
https://www.ncbi.nlm.nih.gov/pubmed/2272331

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