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Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.

The frequency of point mutations at codons 12 and 13 of the c-K-ras gene has been determined in a panel of more than 400 human tumors. Mutant c-K-ras genes were detected in about 75% of adenocarcinomas of the pancreas (n = 84); 40% of adenomas (n = 72) and carcinomas (n = 244) of the colon end rectu...

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Detalles Bibliográficos
Autores principales: Capella, G, Cronauer-Mitra, S, Pienado, M A, Perucho, M
Formato: Texto
Lenguaje:English
Publicado: 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568052/
https://www.ncbi.nlm.nih.gov/pubmed/1685441