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Mechanisms of oncogene cooperation: activation and inactivation of a growth antagonist.

Gene transfer experiments have defined limitations with regard to the ability of individual oncogenes to transform cultured cells to a tumorigenic state. The stable transformation of REF52 cells by either the ras or sis oncogenes requires the continuous expression of a second collaborating oncogene,...

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Detalles Bibliográficos
Autores principales: Ragozzino, M M, Kuo, A, DeGregori, J, Kohl, N, Ruley, H E
Formato: Texto
Lenguaje:English
Publicado: 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568054/
https://www.ncbi.nlm.nih.gov/pubmed/1837777