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Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant.

The three-dimensional structure of the active guanosine triphosphate (GTP)-analogue-containing complex of the H-ras-encoded p21 has been determined. It was necessary to correct the topology of p21 as published earlier. The structure analysis shows all of the interactions between protein and GTP and...

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Detalles Bibliográficos
Autores principales: Wittinghofer, F, Krengel, U, John, J, Kabsch, W, Pai, E F
Formato: Texto
Lenguaje:English
Publicado: 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568068/
https://www.ncbi.nlm.nih.gov/pubmed/1773783