Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.

A poly(ADP-ribose) polymerase inhibitor, benzamide (BA), was found to induce flat revertants of NIH 3T3 cells that had been transformed by human Ha-ras, rat Ki-ras, rat c-raf, and human ret-II. These genes had been amplified in original transformants, but they were completely eliminated by BA. Contr...

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Detalles Bibliográficos
Autores principales: Nagao, M, Nakayasu, M, Aonuma, S, Shima, H, Sugimura, T
Formato: Texto
Lenguaje:English
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568072/
https://www.ncbi.nlm.nih.gov/pubmed/1773788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568072/
https://www.ncbi.nlm.nih.gov/pubmed/1773788

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