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Differences in the pathways for metabolism of benzene in rats and mice simulated by a physiological model.

Studies conducted by the National Toxicology Program on the chronic toxicity of benzene indicated that B6C3F1 mice were more sensitive to the carcinogenic effects of benzene than were F344 rats. A physiological model was developed to describe the uptake and metabolism of benzene in rats and mice. Ou...

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Detalles Bibliográficos
Autores principales: Medinsky, M A, Sabourin, P J, Henderson, R F, Lucier, G, Birnbaum, L S
Formato: Texto
Lenguaje:English
Publicado: 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568104/
https://www.ncbi.nlm.nih.gov/pubmed/2792050