Cargando…
Differences in the pathways for metabolism of benzene in rats and mice simulated by a physiological model.
Studies conducted by the National Toxicology Program on the chronic toxicity of benzene indicated that B6C3F1 mice were more sensitive to the carcinogenic effects of benzene than were F344 rats. A physiological model was developed to describe the uptake and metabolism of benzene in rats and mice. Ou...
Autores principales: | Medinsky, M A, Sabourin, P J, Henderson, R F, Lucier, G, Birnbaum, L S |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
1989
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568104/ https://www.ncbi.nlm.nih.gov/pubmed/2792050 |
Ejemplares similares
-
The effect of dose, dose rate, route of administration, and species on tissue and blood levels of benzene metabolites.
por: Henderson, R F, et al.
Publicado: (1989) -
Mechanistic considerations in benzene physiological model development.
por: Medinsky, M A, et al.
Publicado: (1996) -
Species differences in the metabolism of benzene.
por: Henderson, R F
Publicado: (1996) -
Critical issues in benzene toxicity and metabolism: the effect of interactions with other organic chemicals on risk assessment.
por: Medinsky, M A, et al.
Publicado: (1994) -
Evidence That Humans Metabolize Benzene via Two Pathways
por: Rappaport, Stephen M., et al.
Publicado: (2009)