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Role of the hypothalamo-pituitary-liver axis in sex differences in susceptibility of the liver to toxic agents
At birth testicular androgens irreversibly program brain centers involved in hypothalamopituitary control of hepatic sex-dependent steroid and drug metabolism. This imprinting process results in activation of a hypothalamic “feminostatin”—a secreting center that is turned on just before puberty. Fem...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1981
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568426/ https://www.ncbi.nlm.nih.gov/pubmed/6263606 |