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Model studies in cytochrome P-450-mediated toxicity of halogenated compounds: radical processes involving iron porphyrins.
Haloalkane toxicity originates from attack on biological targets by reactive intermediates derived from haloalkane metabolism by a hemoprotein, cytochrome P-450. Carbon-centered radicals and their peroxyl derivatives are most likely involved. The reactions of iron porphyrin--a model for cytochrome P...
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| Formato: | Texto |
| Lenguaje: | English |
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1985
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568613/ https://www.ncbi.nlm.nih.gov/pubmed/3007100 |