Polyclonal antibodies to quantitate cis-diamminedichloroplatinum(II)--DNA adducts in cancer patients and animal models.

cis-Diamminedichloroplatinum (II) (cis-DDP), the antitumor drug, is cytotoxic in vitro primarily by binding to DNA and disrupting its normal functions. We have studied cis-DDP modification of DNA in nucleated peripheral blood cells (buffy coat cells) of testicular and ovarian cancer patients receivi...

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Detalles Bibliográficos
Autores principales: Poirier, M C, Reed, E, Zwelling, L A, Ozols, R F, Litterst, C L, Yuspa, S H
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568668/
https://www.ncbi.nlm.nih.gov/pubmed/4085451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568668/
https://www.ncbi.nlm.nih.gov/pubmed/4085451

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