Repair of O6-(2-chloroethyl)guanine mediates the biological effects of chloroethylnitrosoureas.

Chloroethylnitrosoureas (CENUs) are alkylating and crosslinking agents used for the treatment of human cancer; they are both mutagenic and carcinogenic. We compared the levels of induction of sister chromatid exchanges (SCEs) and the cytotoxicity of nitrosoureas that alkylate only with CENUs. CENUs...

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Detalles Bibliográficos
Autores principales: Bodell, W J, Aida, T, Berger, M S, Rosenblum, M L
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568685/
https://www.ncbi.nlm.nih.gov/pubmed/4085418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568685/
https://www.ncbi.nlm.nih.gov/pubmed/4085418

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