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Partitioning and lipophilicity in quantitative structure-activity relationships.
The history of the relationship of biological activity to partition coefficient and related properties is briefly reviewed. The dominance of partition coefficient in quantitation of structure-activity relationships is emphasized, although the importance of other factors is also demonstrated. Various...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1985
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568760/ https://www.ncbi.nlm.nih.gov/pubmed/3905374 |