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QSAR analysis and data extrapolation among mammals in a series of aliphatic alcohols.

Concepts of QSAR analysis and biological similarity models are combined for use in extrapolation of LD50 values after IP application of a series of aliphatic alcohols (C1-C5) to mouse, hamster, rat, and guinea pig and rabbit. It has been found that although close correlation exists between LD50 valu...

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Detalles Bibliográficos
Autores principales: Tichý, M, Trcka, V, Roth, Z, Krivucová, M
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568771/
https://www.ncbi.nlm.nih.gov/pubmed/4065071