Chemical cleavage reactions of DNA on solid support: application in mutation detection

BACKGROUND: The conventional solution-phase Chemical Cleavage of Mismatch (CCM) method is time-consuming, as the protocol requires purification of DNA after each reaction step. This paper describes a new version of CCM to overcome this problem by immobilizing DNA on silica solid supports. RESULTS: D...

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Detalles Bibliográficos
Autores principales: Bui, Chinh T, Lambrinakos, Andreana, Babon, Jeffrey J, Cotton, Richard GH
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156887/
https://www.ncbi.nlm.nih.gov/pubmed/12744723
http://dx.doi.org/10.1186/1472-6769-3-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156887/
https://www.ncbi.nlm.nih.gov/pubmed/12744723
http://dx.doi.org/10.1186/1472-6769-3-1

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