Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

BACKGROUND: Wnt/Wingless (Wg) signals are transduced by seven-transmembrane Frizzleds (Fzs) and the single-transmembrane LDL-receptor-related proteins 5 or 6 (LRP5/6) or Arrow. The aminotermini of LRP and Fz were reported to associate only in the presence of Wnt, implying that Wnt ligands form a tri...

Descripción completa

Detalles Bibliográficos
Autores principales: Schweizer, Liang, Varmus, Harold
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156895/
https://www.ncbi.nlm.nih.gov/pubmed/12729465
http://dx.doi.org/10.1186/1471-2121-4-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156895/
https://www.ncbi.nlm.nih.gov/pubmed/12729465
http://dx.doi.org/10.1186/1471-2121-4-4

Ejemplares similares