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Genetic differences in drug metabolism associated with ocular toxicity.

The tissue localization and subcellular distribution of drug-metabolizing enzymes in the eye are described. With the use of inbred strains of mice, the [Ah] complex is shown to be an important experimental system for probing genetic differences in drug metabolism and related drug toxicities. Althoug...

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Detalles Bibliográficos
Autores principales: Shichi, H, Nebert, D W
Formato: Texto
Lenguaje:English
Publicado: 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568975/
https://www.ncbi.nlm.nih.gov/pubmed/7044772