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Genetic differences in drug metabolism associated with ocular toxicity.
The tissue localization and subcellular distribution of drug-metabolizing enzymes in the eye are described. With the use of inbred strains of mice, the [Ah] complex is shown to be an important experimental system for probing genetic differences in drug metabolism and related drug toxicities. Althoug...
Autores principales: | Shichi, H, Nebert, D W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1982
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568975/ https://www.ncbi.nlm.nih.gov/pubmed/7044772 |
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