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Reactive metabolites of phenacetin and acetaminophen: a review
Phenacetin can be metabolized to reactive metabolites by a variety of mechanisms. (1) Phenacetin can be N-hydroxylated, and the resulting N-hydroxyphenacetin can be sulfated or glucuronidated. Whereas phenacetin N-O sulfate immediately rearranges to form a reactive metabolite which may covalently bi...
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| Formato: | Texto |
| Lenguaje: | English |
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1983
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569121/ https://www.ncbi.nlm.nih.gov/pubmed/6339229 |