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Initiation/promotion versus complete carcinogenicity in the rodent liver

4-N-Pyrrolidinylazobenzene (4N) is a close structural analog of the rodent liver carcinogen 4-dimethylaminoazobenzene (DAB). This structural similarity led us to evaluate it for genotoxic activity in vitro. We observed activity for 4N and DAB in the BHK cell transformation assay and subsequently in...

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Detalles Bibliográficos
Autores principales: Ashby, John, Elliott, B. M., Lefevre, P. A., Styles, Jerry, Longstaff, E.
Formato: Texto
Lenguaje:English
Publicado: 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569244/
https://www.ncbi.nlm.nih.gov/pubmed/6873024